Critical Benefits of Cell Invasion Assays

Cell-based assays are crucial for analyzing cell health, cytotoxicity, invasion, migration,  and many other biological and drug-discovery applications and cancer research. A cell invasion assay is one of many different types of assays. It measures cell movement across extracellular boundaries and how single cells respond to various chemo-attractants. This blog post will provide an overview of the critical benefits of cell invasion assays. 

Photolithography & Adhesion 

A common problem that can occur during photolithography fabrication is adhesion of the photoresist to the substrate. A photoresist consists of a resin, sensitizer, adhesion promoter, and a thinner. Each component contributes to the overall photoresist properties. A resin is included to withstand an etchant solution that may be used in the later stages of fabrication. A sensitizer offers a photosensitive element to the resist that allows it to be exposed in certain areas and not in others. A thinner is included to modify the viscosity of the overall photoresist and make it easier to spin-coat onto the substrate. The included adhesion promoter is often not potent enough to provide enough strength between resist and substrate material.  

What is Shadow Masking? 

In semiconductor fabrication, stencil metal plates or shadow masks can be used to designate where a metal is deposited upon a substrate. The stencil serves as a medium for achieving custom designs onto a substrate without the need for photolithography processes. This works by masking certain areas of a substrate while exposing others to be deposited with metal.  

Emerging Technologies – Internet-of-Things

Internet of things (IoT) encompasses physical things that connect and exchange data with other technology. IoT offers increased connectivity, cloud computing, machine learning, and advancements to AI. Emerging advancements in IoT include machine monitoring, wearable health monitoring, inventory management, and public safety enhancements. IoT works through device-to-device communications that is conducted through sensor technology and actuators.  

What is a Cleanroom?

You might be thinking a cleanroom refers to an organized and tidy space. However, a certified cleanroom is much more than that. A cleanroom is a space for conducting operations that are sensitive the particle contamination, such as semiconductor fabrication. Enviornmental factors are altered in order to provide a controlled clean atmosphere. Airborne particles are filtered out while temperature, humidity, and air flow are regulated.  

Custom Dicing Service

Platypus Technologies offers a customizable dicing service for a range of substrate materials. Accommodations can be made for both silicon wafers and glass substrates. Substrates are scribed, and then broken into individual pieces. Well-defined scribing lines are made with a diamond finished scribing wheel. This process does not involve heat therefore prevents any potential damage to a substrate material. 

Creating patterns through Metal Lift-off

Creating a patterned metal on a substrate can be done through various methods. Metal lift-off represents just one fabrication method that entails three steps: 1) patterning a photosensitive polymer film onto the target substrate, 2) metal deposition onto the patterns polymer film, and 3) removal of polymer with a solvent.  

Thin-film Metal Coatings

As more advancements are made in the electronics industry, thin-film metal coatings remain in high demand. The team at Platypus Technologies has done custom work with a range of companies, from completing small R&D projects to creating continual partnerships. Our credibility has been built based on our internal expertise, high-quality metal deposition, and attention to detail.  

How Thin Films Factor into Surface Science

Thin films are used in a wide range of advanced applications in surface science, and studies surrounding thin films have significantly advanced solid state chemistry and physics. Surface science relates to any surfaces, interfaces and their applications and any research or development in the field. Thin films play a large part in surface science, and this blog post aims to cover how and why.

What is Plasma Cleaning?

Reactive gas molecules form what is known as plasma. The ions and electrons in plasma are used to remove unwanted organic contaminants. Unwanted particles are removed through a vacuum system. This cleaning procedure creates an ideal sterilization process. In addition, plasma cleaning eliminates the need for expensive solvents since substrate surfaces can be cleaned via a chemical reaction within plasma molecules.  

Applications Of Wound Healing Assays

Wound healing assays measure cell migration over a two-dimensional (2D) monolayer. As cell migration takes place throughout numerous physiological processes, it has been studied in a variety of contexts from tissue injury, wound healing, cancer metastasis and more. Throughout the following post, we will explain the applications of wound healing assays and the importance of each.

What is the Difference Between Invasion and Cell Migration Assays?

Many biomedical research projects revolve around analysis of the cell. Information about cell types, cell proliferation, cell count, and cell migration is critical to advancing disease treatment and health studies. To extract this knowledge, scientists rely on various types of assays that focus on characterizing a specific property or function of target cell types. This blog post will provide a brief overview of the difference between invasion and cell migration assays, with an emphasis on cell migration assays from Platypus Technologies.

What is a Disk Electrode Used For?

Disk electrodes are one of the essential components for performing many electrochemical experiments. Measurements such as cyclic voltammetry are widely used methods for the characterization of nearly any material or process that involves electron transfer – something ubiquitous in any material or component that will be used as part of an electronic system.

Advantages and Disadvantages of Photolithography

Photolithography, also known as optical lithography, is a microfabrication technique that uses light to produce precisely patterned thin films over substrates such as silicon wafers. These patterned films typically protect selected areas of the underlying substrate during subsequent processing, such as etching or metal deposition.

Advancements in Precision Fluid Dispensing System Technology

Automation and Robotics Allow for Higher Precision in Industrial Fluid Dispensing Applications

Precision fluid dispensing systems are utilized in a range of advanced manufacturing applications. At Platypus Technologies, we employ advanced fluid dispensing technology in our biosensor and bioassay fabrication processes, as well as in our conformal coating solutions.