Our Mission:

Empowering Scientists to Solve Our Greatest Challenges

Our Services

Custom solutions for research, product development and manufacturing

Engineering Design

Design sensors, biosensors, electrodes and microfluidic templates

Metal Coatings

Deposition of thin films of gold, platinum, silver, aluminum, copper and more.

Surface Patterning

Fabricate devices via photolithography, wet etching and lift-off.

Singulation

Discover our capabilities for wafer and glass cutting.

Our Vision:

Creating innovative surface science-based solutions that drive human progress

Custom Solutions by Platypus Technologies

Have a special project in mind? We can help! Our team has extensive experience creating biosensors, chemical sensors, microfluidic devices, and more.

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The Latest From Platypus Technologies

Transwell Assays: Pros, Cons, and Alternatives

Transwell assays are a mainstay in cell biology research and are instrumental in studying cellular migration and cell invasion. A permeable membrane simulates a cellular barrier. If cells migrate through it then these can be stained, for instance with crystal violet, and kept at room temperature. This will be in a 24-well plate. The membrane then needs to be cleaned with distilled water before the migratory cells can be calculated.  With that completed, an assessment can be made about cell fixation compared to how many cells have migrated. Through this process, transwell assays can provide insights into the mechanisms of cancer cells and their metastasis. It can also offer an understanding of tissue repair and cellular communication. This article provides an in-depth analysis of transwell assays, examining their advantages, limitations, and exploring alternative methodologies.

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How to Perform a Cell Migration Assay

Cell migration is a fundamental process in a variety of biological phenomena. This includes embryonic development, tissue regeneration, immune responses, and cancer metastasis. Understanding cell migration mechanisms is crucial for advancing therapeutic strategies in wound healing, immune therapies, and cancer treatment. Cell migration assays can help with the examination of the migratory responses of cells under various conditions.  This blog post delves into the methodology of conducting a cell migration assay. It focuses on the scratch assay, one of the most common and straightforward methods to assess cell migration in vitro.

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