What is the Difference Between Invasion and Cell Migration Assays?

Many biomedical research projects revolve around analysis of the cell. Information about cell types, cell proliferation, cell count, and cell migration is critical to advancing disease treatment and health studies. To extract this knowledge, scientists rely on various types of assays that focus on characterizing a specific property or function of target cell types. This blog post will provide a brief overview of the difference between invasion and cell migration assays, with an emphasis on cell migration assays from Platypus Technologies.

What is a Disk Electrode Used For?

Disk electrodes are one of the essential components for performing many electrochemical experiments. Measurements such as cyclic voltammetry are widely used methods for the characterization of nearly any material or process that involves electron transfer – something ubiquitous in any material or component that will be used as part of an electronic system.

Advantages and Disadvantages of Photolithography

Photolithography, also known as optical lithography, is a microfabrication technique that uses light to produce precisely patterned thin films over substrates such as silicon wafers. These patterned films typically protect selected areas of the underlying substrate during subsequent processing, such as etching or metal deposition.

Why Is There a Shortage of Silicon Chips?

Silicon chips are a type of integrated circuit that is the primary electronic component of computing devices. The chips are mainly made from silicon (as the name suggests), which is the second most abundant element on the earth. In the last few years, there has been a significant shortage of silicon chips across the world. In this article, we explain the reasons why and the effects of this shortage.

The Evolution of Cell Culture Surfaces

Cell culture surfaces are surfaces on which cells are grown under controlled conditions away from their natural environment. The cells under investigation are isolated from the tissue and are sustained and preserved under carefully controlled conditions. 

The History of Cell Culture Surfaces

In the past century, cell culture, growth, and differentiation have moved from fringe experiments to a widely used bioproduction tool. In this time, the cell culture surfaces themselves have evolved as the research requirements adjust. 

How are Silicon Wafers Used in Electrochemistry

Silicon wafers are materials that are used for the production of semiconductors. They can be found in many types of electronic devices that are used in everyday life. Silicon wafers are super-flat disks that are refined into a mirror-like surface, they are extremely clean and free from impurities and micro-particles.

Silicon wafers are particularly well suited to use in electronic devices because electrical currents can pass through silicon conductors than many other materials. Here we will explore more about the uses of silicon wafers in electrochemistry and some of their key characteristics.

What are the Steps in Cell Migration

Cell migration is an extremely important cellular process. It is the directed movement of a group of cells or a single cell when responding to chemical and mechanical signals. This fundamental process takes place throughout life and continues until death, contributing to pathogenic states in disease. This article will outline the key steps of the process and how they work.

Using Photolithography for Surface Patterning

What is Photolithography?

Photolithography, sometimes known as optical lithography or UV lithography is a process that is used in microfabrication for surface patterning parts of a thin film or the bulk of a substrate. Photolithography uses light to transfer a geometric pattern from a photomask to a light-sensitive chemical photoresist or simply resist on the substrate.

An Introduction to Wound Healing Assays

Wound healing assays are standard in vitro methods of probing collective cell migration in two dimensions. In wound healing assays, a cell-free area is formed in a confluent monolayer using physical exclusion or taking away the cells from the area via thermal, chemical, or mechanical damage. It is exposure to this cell-free area that leads to cells migrating into the gap.

The Basics of Surface Science: Nanoscale Chemistry & Physics

Surface science is a highly complex field that spans multiple disciplines and is related to the chemical and physical interactions that take place when two phases come together. These interfaces can be solid-vacuum, liquid-gas, solid-liquid, solid-gas, etc. This article will outline some of the basic elements of surface science and how it is used.

What is Compound Screening in Drug Discovery?

Developing a new medicine and bringing it to market is a long, difficult and expensive process. This process begins with drug discovery:  the unearthing of promising compounds which demonstrate some beneficial biological effect. Compound screening is the primary method by which initial drug discovery is carried out.

Custom Metal Coatings—When to Use Aluminum Thin Films

Functional metal coatings are increasingly important in research settings, enabling scientists to modulate the surface properties of different substrates to suit specific experiment parameters. Yet coated microscope slides are not a new phenomenon. Biochemists and life scientists have long exploited polymeric coatings like epoxy resin, gelatine, poly-L-lysine, and various silanes to promote better adhesion between organic samples and a substrate. Custom metal coatings are a natural progression of polymer-coated microscope slides for a more precise era of life science microscopy.

OEM Silicon Chips & Wafers for Biosensors

New human health challenges arise in response to an array of geopolitical and socioeconomical factors including radical global population growth, paradigm shifts in social behaviour, or increased urbanization and loss of land for agriculture. This creates unique opportunities for innovators and original manufacturers (OEMs) who are willing to collaborate and deliver solutions to the next generation of environmental and human health problems.