CYTO 2011

High Content Analysis of a Robust 384-Well Cell Migration Assay

Sean Burke¹, Tim Baranowsk², Jennifer A. Fronczak³, Jayne Hesley², Keren I. Hulkowerv, David Novo¹

¹ De novo Software, Inc. Los Angeles, CA, ² Molecular Devices, Inc. Sunnyvale, CA,
³ Platypus Technologies, LLC, Madison, WI

SBS 2011

Oris™ Pro 384 Cell Migration Assays run on IN Cell Analyzer 6000

Robert Graves¹, Keren I. Hulkower², HaiGuang Zhang¹ and June Davies¹

¹GE Healthcare, Piscataway, NJ; ²Platypus Technologies, LLC. Madison, WI

Assay Performance with IN Cell Analyzer 6000

Robert Graves¹, Erwen Mei¹, Pavel Fomitchov¹, Dan Manning¹, Suzanne Hancock², John Picot¹, Jun Li¹, and Mark Campion¹

¹GE Healthcare, 800 Centennial Ave, Piscataway, NJ 08855; GE Healthcare,
²Amersham Place, Little Chalfont, Buckinghamshire, England, UK,

“High Content Analysis of an Automatable 3-Dimensional Cell Invasion Assay”

By Renee L. Herber¹, Jennifer A. Fronczak¹, Timothy Baranowski², Keren I. Hulkower¹

¹Platypus Technologies, LLC, Madison, WI 53711, USA
²Molecular Devices, Inc., Sunnyvale, CA 94089, USA

AACR 2011

Automation of both sample preparation and analysis of a cell migration assay

Sarah E. Burroughs¹, Keren I. Hulkower², Simone Schicktanz³, Jennifer A. Fronczak², Karin Boettcher³, and Timothy E. Cloutier¹

¹PerkinElmer, Downers Grove, IL;
²Platypus Technologies, Madison, WI;
³PerkinElmer, Hamburg, Germany

“A Robust 384-Well Cell Migration Assay for High Content Analysis of Cells Treated with Anti-Cancer Therapeutics”

Jennifer A. Fronczak¹,Keren I. Hulkower¹,Andreas Vogt²

¹Platypus Technologies, LLC, Madison, WI 53711, USA
²University of Pittsburgh Drug Discovery Institute, Pittsburgh, PA 15260, USA

HCA 2011

"High Throughput Imaging Assay to Assess Cell Migration"

By Jayne Hesley¹, Keren Hulkower², Paula Gedraitis¹ and Pierre Turpin¹

¹Molecular Devices, Inc., Sunnyvale, CA; ²Platypus Technologies, LLC, Madison, WI

Oris™ Pro Cell Migration and Invasion Assays run on IN Cell Analyzer 2000

HaiGuang Zhang¹, Keren I. Hulkower² and Robert Graves¹

¹GE Healthcare, 800 Centennial Ave, Piscataway, NJ 08855;
²Platypus Technologies, LLC. 5520 Nobel Dr., Suite 100, Madison, WI 53711

"A Robust 384‐Well Cell Migration Assay for High Content Analysis"

Jennifer A. Fronczak*, Jesse R. Finer*, Scott Gehler*, Andreas Vogt§, Keren I. Hulkower*

*Platypus Technologies, LLC, 5520 Nobel Drive, Suite 100, Madison, WI 53711, USA
§University of Pittsburgh Drug Discovery Institute, 10047 BST‐3, 3501 Fifth Avenue, Pittsburgh, PA 15260, USA

ASCB 2010

"Identification of stimulators and inhibitors of cell migration in human embryonic stem cell derived neural progenitors using a novel, high throughput amenable assay platform"

Allan C. Powe, Jr.*, Kathryn L. Hodges*, Jamie M. Chilton*, Scott Gehler§, Renee L. Herber§, Keren I. Hulkower§, Steven L. Stice*

*ArunA Biomedical, Inc. 425 River Road, Athens, GA 30606; §Platypus Technologies, LLC, 5520 Nobel Drive, Suite 100, Madison, WI 53711, USA

HCA 2010

"Measuring of migration in a fully automated image based approach."

Simone Schicktanz, Hartwig Preckel and Olaf Deppe.
PerkinElmer Cellular Technologies, Germany, GmbH, D. Hamburg
Keren Hulkower
Platypus Technologies LLC, Madison, WI, USA

SBS 2010

"A Novel Automatable Cell Migration Assay for High Content Screening."

Scott R. Gehler, Jennifer A. Fronczak, Keren I. Hulkower, Joseph K. Burkholder
Platypus Technologies LLC, Madison, WI, USA

"Measuring of migration in a fully automated imaging based approach."

Simone Schicktanz, Hartwig Preckel, Olaf Deppe and Karin Boettcher
PerkinElmer Cellular Technologies, Germany, GmbH, D. Hamburg
Keren Hulkower
Platypus Technologies LLC, Madison, WI, USA

"A Novel Cell Migration Assay for High Content Analysis."

"Oris™ Pro: A Novel Automatable Cell Migration Assay for High Content Screening."

Scott R. Gehler, Jennifer A. Fronczak, Keren I. Hulkower, and Joseph K. Burkholder

Platypus Technologies LLC, Madison, WI, USA

ASCB 2009

"Characterization of a Cell Invasion Assay for High Content Screening."

KI Hulkower¹, D Onley², P Wylie²

¹Platypus Technologies LLC, Madison, WI, ²TTP LabTech Ltd, Melbourn, Herts, United Kingdom

Lab Automation 2009

"Optimizing Robustness of the Membrane-free, Oris™ Cell Migration Assay for High Throughput Screening using the BioTek Synergy™ HT Multi-Mode Microplate Reader."

KI Hulkower¹, RL Herber¹, S Gehler¹, P Held², X Amouretti²

¹Platypus Technologies LLC, Madison, WI, ²BioTek Instruments, Inc., Winooski, VT

Lab Automation 2009

"A Novel High Throughput-Compatible Cell Migration Screening Assay using an Acumen ^eX3."

Paul Wylie, Scott Gehler* and Keren Hulkower*

TTP LabTech Ltd, Melbourn science Park, Melbourn, Royston, Herts SG8 6EE, UK.
* Platypus Technologies LLC, 5520 Nobel Drive, Suite 100, Madison, WI, US

"Substrate Dependent Effects of c-Met Inhibitors on HGF-induced Cell Migration."

KI Hulkower¹, SR Soltaninassab¹, KM Anhalt¹, RL Herber¹, K Moin², BF Sloane²

¹ Platypus Technologies LLC, Madison, WI,
² Department of Pharmacology & Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI

"Substratum-dependent Effects of ROCK and Myosin Inhibitors During 2D and 3D Migration of Breast Epithelial Cells."

Scott Gehler^1,2, Keren I. Hulkower², Renee L. Herber² and Patricia J. Keely^{1 1}Department of Pharmacology, University of Wisconsin, Madison, WI 53706,
²Platypus Technologies LLC, Madison, WI, 53711

"A Novel 96-well Assay for Assessing Chemokinetic Modulators of Cell Migration and Invasion."

"A Novel High Throughput-Compatible Cell Migration Screening Assay."