Oris™ Pro Cell Migration Assays

Fully Automatable Cell Migration Assays

Exclusion zone technology ensures consistent initial cell-free regions for accurate, reproducible quantification of cell movement:

Pre-migration and Post-migration slides

  • Industry-standard 96- and 384-well formats
  • Real-time monitoring
  • Quantification with plate readers, microscopes, or high-content imagers
  • No artificial membranes
  • High Z-factors in screening studies

Oris™ Pro assays use a soluble gel to create a central cell-free detection zone in the center of each well of 96- or 384-well plates, facilitating the simplest assay design and full automation.

Oris™ Pro Cell Migration Assays use a soluble gelThe product consists of 96- or 384-well plates with a spot of gel in the center of each collagen Icoated or tissue culture treated well. To use, simply:

  1. Seed cells directly in the wells manually or with an automated robot
  2. Allow cells to adhere to the bottom of the wells
  3. Start monitoring cell migration

As with all Oris™ products, you can monitor cell behavior in real time and quantify the results using plate readers, microscopes, or high content imagers.

Oris™ Pro 384-well plates are priced for high throughput screening.

Sample Data

Slides of HT1080 cells seeded Oris™ Pro Cell Migration Assays
HT1080 cells were seeding in the Oris™ Pro 96-well and 384-well collagen I coated plates at 30,000 and 5,000 cells per well respectively. Cells were treated for 24 hours with the actin polymerization inhibitor Cytochalasin D, fixed, and stained for F-actin. Images were acquired using a Zeiss Axio Observer.Z1 inverted microscope. Migration was quantified by measuring percent area closure in the exclusion zone.
Oris™ Pro Cell Migration Assays Chart - Dose-response curves
Dose-response curves and IC50 values were generated after averaging four wells per data point.

Order the Oris™ Pro Cell Migration Assay

Product NumberProduct DescriptionPrice
PROCMA1Oris™ Pro Cell Migration Assay, 1-pack$189
PROCMA5Oris™ Pro Cell Migration Assay, 5-pack $880
PROCMACC1Oris™ Pro Cell Migration Assay - Collagen I Coated, 1-pack$209
PROCMACC5Oris™ Pro Cell Migration Assay - Collagen I Coated, 5-pack$950
PRO384CMA1Oris™ Pro 384 Cell Migration Assay, Tissue Culture Treated, 1-plate evaluation pack$269
PRO384CMA5Oris™ Pro 384 Cell Migration Assay, Tissue Culture Treated, 5-plate evaluation pack$1260
PRO384CMACC1Oris™ Pro 384 Cell Migration Assay, Collagen I Coated, 1-plate evaluation pack$279
PRO384CMACC5Oris™ Pro 384 Cell Migration Assay, Collagen I Coated, 5-plate evaluation pack$1300

Oris™ is a trademark of Platypus Technologies, LLC. Oris™ Pro technology is patent pending.
View Platypus’ Terms and Conditions.